Thursday, October 22, 2015

UQ Pharmacy School Pharmacometrics

Pharmacometrics at the UQ School of Pharmacy

The Pharmacometrics group at the UQ School of Pharmacy includes internationally recognised researchers that have a diverse range of interests in the area of pharmacometrics.

UQ Pharmacy School
UQ School of Pharmacy facilities

Pharmacometrics refers to the analysis of experiments and clinical studies, in particular pharmacokinetic and pharmacodynamic studies (PKPD) for the purposes of quantitation of drug clearance in the body, drug effects and side effects, disease progression, the optimisation of study designs, and Pharmacometric research focuses on nonlinear mixed effects (“population”) models.

Such models describe data, generally is the response-time profiles observed in a clinical trial, by a basic model, accounting for the general structure of the underlying system, and a set of hierarchical variability components, accounting for variability between subjects, within subjects over time and remaining between observation variability.

Research at the Pharmacometrics group can be divided into two main areas:
  1. The analysis of dose-concentration-response data from trials and clinical therapeutic drug monitoring data to understand therapies with existing drugs with the aim of allowing improved therapy and individualized therapy and
  2. The utilization of the developed models for the purpose of designing future prospective studies, deciding upon dosing strategies and other developmental decisions.
UQ School of Pharmacy mainly tries to employ the Population Pharmacometrics approach to answer questions arising from the clinical setting and work closely together with several clinical teams in Brisbane and worldwide.

Research Areas

The staff members in this group have interests in the supervision and development of academic and contract research projects in one or more of the following key areas:
Optimising drug therapy for
  • Antibiotics
  • Infectious diseases
    • critical care
    • cystic fibrosis
    • malaria
    • sepsis
    • tuberculosis/HIV
    • solid organ transplantation
    • Immunosuppressant agents
  • Effects of body composition on pharmacokinetics
    • obese patients
    • paediatrics
    • oncology
  • Pharmacogenomic subgroups
Software used
  • NONMEM
  • PsN, WFN
  • Xpose, R,
  • PopED, WinPOPT
  • Monolix
  • Berkley Madonna

Would you like to study pharmacy at the University of Queensland?

The Bachelor of Pharmacy (Honours) program is a well-established, professionally accredited learning framework that is well received by both students and the profession. The program has evolved into one of the country’s most comprehensive and well-respected pharmacy degrees, both domestically and internationally. This undergraduate program runs over 4 years, full time, after which graduates are eligible to complete a 48-week paid internship in either community or hospital pharmacy.

Program: Bachelor of Pharmacy (Honours)
Location: Brisbane, Queensland
Semester intake: February
Duration: 4 years
Application deadline: November 15, 2015

Entry Requirements
Applicants to UQ Pharmacy are required to have completed their high school diploma. Applicants should have completed Grade 12 English, Chemistry and Math to meet program prerequisites.

If you have commenced or completed a university degree or any post-secondary studies, your most recent studies will be assessed in terms of your grades. If you have not completed the necessary prerequisite subjects in your post-secondary studies, your high school transcripts will then be assessed for prerequisite subjects.

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